RHA® Collection
Designed for Dynamics
RHA® Collection
Designed for Dynamics
RHA® is Resilient Hyaluronic Acid, and represents the latest advancement in HA filler science: designed for dynamic wrinkles and folds to help you keep your patients looking beautiful at rest, and flawless in motion.
Indications and Important Safety Information
The RHA® collection of resilient hyaluronic acid (HA) fillers includes RHA® 2, RHA® 3 and RHA® 4. RHA® 2 and RHA® 3 are indicated for injection into the mid-to-deep dermis for the correction of moderate to severe dynamic facial wrinkles and folds, such as nasolabial folds; and RHA® 4 is indicated for injection in the deep dermis to superficial subcutaneous tissue for the correction of moderate to severe dynamic facial wrinkles and folds, such as nasolabial folds; in adults 22 or older.READ MORE
RHA® is the first and only resilient hyaluronic acid filler designed for facial dynamics.


Introducing The 4th Dimension of Facial Aesthetics: Dynamics
The RHA® collection is designed to adapt to the dynamic demands of the face, for a look that’s beautiful at rest and flawless in motion.

Innovative Preserved Network Technology
The RHA® Collection is formulated to be more like natural HA found in the skin.
Preserved Network Technology preserves HA chain length and intrinsic non-covalent bonds to more closely resemble natural HA.

No Compromise
The RHA® Collection offers both
duration and long-term safety
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Proven clinical effectiveness and duration up to 15 months*†
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No delayed-onset treatment-related adverse events observed in the US clinical studies*
*Clinical effectiveness and safety were demonstrated in 2 pivotal studies, each a 15-month, randomized, double-blinded, within-subject, multicenter, noninferiority, prospective trial. Study 1 (174 subjects): 74 RHA® 2/control treatment group, 74 RHA® 3/control treatment group, and 26 no-treatment group. Study 2 (140 subjects): 120 RHA® 4/control treatment group and 20 no-treatment group.
†Duration based on blinded evaluator assessments at Month 15 in the 2 pivotal studies, the percentages of responders ( ≥ 1 grade improvement on the wrinkle severity rating scale) were 80.9% for RHA 2, 78.7% for RHA 3, and 89.2% for RHA 4.
RHA® is the Latest Innovation in HA Technology
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Early dermal filler products based on bovine and human collagen
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Restylane® NASHA™ technology approved in the EU to address deep wrinkles
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Juvéderm® Hylacross™ technology is approved in the EU for addressing wrinkles and folds
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Juvéderm® Vycross™ technology approved in the EU for volumizing
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Emervel® with OBT™ technology approved in the EU (later launched in the US as Refyne® and Defyne® for static expression).
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RHA® changes the game in Europe with gel designed for dynamic wrinkles and natural expressions
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RHA® available in the US for dynamic wrinkles and folds - the 4th dimension